Y: The Last Man Single Issues Series by Brian K. Vaughan, Pia Guerra, José Marzán Jr., Pamela Rambo, Clem Robins

"Unmanned (Part I of V)"Written by Brian K. Vaughan (Lost, EX MACHINA), this is the saga of Yorick Brown - the only human survivor of a planet-wide plague that instantly kills every mammal with a Y chromosome. Accompanied by his pet monkey, Yorick searches for his lost love...and the answer to why he's the last man on earth.

When a mysterious plague kills all male life on the planet, what do women do with the billions of corpses? Yorick Brown discovers the horrific answer as he travels to Washington in search of his Congresswoman mother. And which unexpected female has just been named President of the United States?

In this emotional issue, Yorick joins hundreds of women at a famous monument to pay tribute to all of the men who died in the Plague. But when a pack of violent female extremists interrupts this memorial service, the last man on Earth may end up joining his fallen brothers...

In this perfect jumping-on point for new readers, Yorick Brown and his companions embark on an important quest. Riding the rails across a radically transformed America, the last man on earth is pursued by several competing factions, including the deadly Daughters of the Amazon.

Yorick Brown is the last man on Earth…but is he the last man in the solar system? That question is raised when a mysterious visitor lands on top of Yorick’s speeding train. Plus, the identity of the shadowy informant is finally revealed.

A mysterious young Russian woman leads Yorick Brown and his companions to a Kansas farm that may be more than meets the eye. Meanwhile, Yorick’s Israeli pursuers finally find their prey…and, 220 miles above Earth, violence breaks out onboard the International Space Station.

As a Soviet escape vehicle leaves the International Space Station, chaos erupts below. Five women risk their lives to make sure that Yorick Brown, the only man on Earth, is not the last. And the terrifying, true motivation of Yorick’s foreign pursuers is finally revealed.

Take three astronauts, one surface-to-air missile launcher, and a pair of Mossad-issue handcuffs…and you’d only have half the ingredients of the last man on earth’s most dangerous escape act.

The fate of the two male astronauts who’ve been trapped in space is finally revealed, and the unmanned world will never be the same. Plus, Yorick Brown has one last confrontation with his foreign pursuers, and Agent 355 reveals her true feelings for the young man that she’s vowed to protect.

In part 1 of the 2-part “Comedy & Tragedy,” find out what art and entertainment might be like in a world without men. The female performers of the Fish & Bicycle Traveling Theater Company are doing what they can to carry on, but what could their work have to do with the last man on Earth?

It’s opening night of the all-female Fish & Bicycle Theater Company’s controversial new play. But if a mysterious visitor from Japan gets her way, the show may have the shortest run in the history of modern drama. When the curtain finally falls, will anyone be alive to see it?

In part 1 of a 3-part story, Yorick and his companions travel to Colorado, hoping to find medical attention for ailing pet monkey Ampersand. After an explosive encounter with a posse of female marshals, the group takes shelter with a retired agent of the mysterious Culper Ring. Can they trust her?

Travel inside the mind of the last man on Earth! What is Yorick Brown’s deepest, darkest secret, and what does it have to do with a swarm of New York City houseflies? One very domineering woman intends to do whatever it takes to find out—whether Yorick likes it or not!

What really happened to Yorick Brown in the first days after the Plague killed every other male on earth? Find out, as this psychosexual journey through the memories of the last man comes to a haunting end.

Yorick, Agent 355, Dr. Mann and Ampersand hit the road again on their way to San Francisco, but a pit stop in Arizona finds them face-to-face with an anti-American (and heavily-armed) militia made up of female survivors who believe that the U.S. government is responsible for the death of all men.

It’s guns, alcohol, and a monkey as the last man on Earth’s standoff with the female survivors of an Arizona militia group continues. Yorick grows closer to one particular member—and Dr. Mann reveals a horrific secret.

The last man on earth’s confrontation with the female survivors of a violent militia group comes to an end. Plus, an unexpected guest arrives, and the status quo of the unmanned world is forever changed.